Abstract
The incidence of electroencephalographic (EEG) abnormalities in Multiple Sclerosis (MS) patients, as reported in literature, varies from 20 to 50%. The recent development of EEG computerized analysis allows to increase the sensitivity of the EEG technique. In this study EEG mapping was performed in 48 clinically probable or definite MS patients and neurophysiological results were correlated with clinical, neuropsychological and brain Nuclear Magnetic Resonance Imaging (NMRI). EEG mapping was abnormal in 40% of the cases: eleven patients showed increased Delta Relative Power (RP), 16 increased Theta RP, 13 decreased Alpha RP and 14 reduced median frequency. Brain NMRI detected areas of abnormal signal in all patients, while at least one neuropsychological test was abnormal in 25 patients (52%). Patients with abnormal EEG, if compared to the others, showed a lower memory (p <0.05) and higher demyelinating lesional scores (p <0.004), a more severe ventricular dilatation (p <0.05) and a more relevant corpus callosum atrophy (p <0.02).
| Original language | Italian |
|---|---|
| Pages (from-to) | 233-237 |
| Number of pages | 5 |
| Journal | Rivista di Neurobiologia |
| Volume | 39 |
| Issue number | 3 |
| Publication status | Published - 1993 |
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ASJC Scopus subject areas
- Neuroscience(all)
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MAPPE EEG NELLA SCLEROSI MULTIPLA. / Locatelli, T.; Filippi, M.; Martinelli, V.; Rodegher, M.; Magnani, G.; Scotti, G.; Comi, G.
In: Rivista di Neurobiologia, Vol. 39, No. 3, 1993, p. 233-237.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - MAPPE EEG NELLA SCLEROSI MULTIPLA
AU - Locatelli, T.
AU - Filippi, M.
AU - Martinelli, V.
AU - Rodegher, M.
AU - Magnani, G.
AU - Scotti, G.
AU - Comi, G.
PY - 1993
Y1 - 1993
N2 - The incidence of electroencephalographic (EEG) abnormalities in Multiple Sclerosis (MS) patients, as reported in literature, varies from 20 to 50%. The recent development of EEG computerized analysis allows to increase the sensitivity of the EEG technique. In this study EEG mapping was performed in 48 clinically probable or definite MS patients and neurophysiological results were correlated with clinical, neuropsychological and brain Nuclear Magnetic Resonance Imaging (NMRI). EEG mapping was abnormal in 40% of the cases: eleven patients showed increased Delta Relative Power (RP), 16 increased Theta RP, 13 decreased Alpha RP and 14 reduced median frequency. Brain NMRI detected areas of abnormal signal in all patients, while at least one neuropsychological test was abnormal in 25 patients (52%). Patients with abnormal EEG, if compared to the others, showed a lower memory (p <0.05) and higher demyelinating lesional scores (p <0.004), a more severe ventricular dilatation (p <0.05) and a more relevant corpus callosum atrophy (p <0.02).
AB - The incidence of electroencephalographic (EEG) abnormalities in Multiple Sclerosis (MS) patients, as reported in literature, varies from 20 to 50%. The recent development of EEG computerized analysis allows to increase the sensitivity of the EEG technique. In this study EEG mapping was performed in 48 clinically probable or definite MS patients and neurophysiological results were correlated with clinical, neuropsychological and brain Nuclear Magnetic Resonance Imaging (NMRI). EEG mapping was abnormal in 40% of the cases: eleven patients showed increased Delta Relative Power (RP), 16 increased Theta RP, 13 decreased Alpha RP and 14 reduced median frequency. Brain NMRI detected areas of abnormal signal in all patients, while at least one neuropsychological test was abnormal in 25 patients (52%). Patients with abnormal EEG, if compared to the others, showed a lower memory (p <0.05) and higher demyelinating lesional scores (p <0.004), a more severe ventricular dilatation (p <0.05) and a more relevant corpus callosum atrophy (p <0.02).
KW - EEG
KW - mapping
KW - multiple sclerosis
UR - http://www.scopus.com/inward/record.url?scp=0027880315&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027880315&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0027880315
VL - 39
SP - 233
EP - 237
JO - Rivista Italiana di Neurobiologia
JF - Rivista Italiana di Neurobiologia
SN - 0035-6336
IS - 3
ER -