Modificazione del segnale EEG nei topi DBA/2J dopo trattamento agonistico e antagonistico dei recettori GABAB

F. Santoni; G. P. Mereu; M. Fà; G. Carta; A. Meloni; V. Ghiglieri; F. Genugu; M. Puligheddu; L. Barberini; F. Marrosu

Modificazione del segnale EEG nei topi DBA/2J dopo trattamento agonistico e antagonistico dei recettori GABAB

Translated title of the contribution: EEG variations following GABAB agonist and antagonist treatment in DBA/2J mice

F. Santoni, G. P. Mereu, M. Fà, G. Carta, A. Meloni, V. Ghiglieri, F. Genugu, M. Puligheddu, L. Barberini, F. Marrosu

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

DBA/2J mice present spontaneous spiking activity resembling the petit-mal in humans and mainly dependant by GABAB receptors. The present study address the digital EEG analysis of the spike composition versus the seizure activity induced or reduced by agonists and antagonists respectively. Moreover, the profile of Levetiracetam (LEV), a new anticonvulsant, has been described accordingly. A further and correlated analysis investigate the modifications of the EEG background in the above conditions using an original algorhythm.

Translated title of the contribution	EEG variations following GABAB agonist and antagonist treatment in DBA/2J mice
Original language	Italian
Pages (from-to)	317-319
Number of pages	3
Journal	Bollettino - Lega Italiana contro l'Epilessia
Issue number	121-122
Publication status	Published - Jul 2003

ASJC Scopus subject areas

Clinical Neurology

Cite this

@article{bc81d0408bf64ef6990beff4f8368c66,

title = "Modificazione del segnale EEG nei topi DBA/2J dopo trattamento agonistico e antagonistico dei recettori GABAB",

abstract = "DBA/2J mice present spontaneous spiking activity resembling the petit-mal in humans and mainly dependant by GABAB receptors. The present study address the digital EEG analysis of the spike composition versus the seizure activity induced or reduced by agonists and antagonists respectively. Moreover, the profile of Levetiracetam (LEV), a new anticonvulsant, has been described accordingly. A further and correlated analysis investigate the modifications of the EEG background in the above conditions using an original algorhythm.",

keywords = "Baclofen, DBA2J Mice, Digital EEG, Levetiracetam, SCH 50911",

author = "F. Santoni and Mereu, {G. P.} and M. F{\`a} and G. Carta and A. Meloni and V. Ghiglieri and F. Genugu and M. Puligheddu and L. Barberini and F. Marrosu",

year = "2003",

month = jul,

language = "Italian",

pages = "317--319",

journal = "Bollettino - Lega Italiana contro l'Epilessia",

issn = "0394-560X",

publisher = "Lega Italiana contro l'Epilessia",

number = "121-122",

}

TY - JOUR

T1 - Modificazione del segnale EEG nei topi DBA/2J dopo trattamento agonistico e antagonistico dei recettori GABAB

AU - Santoni, F.

AU - Mereu, G. P.

AU - Fà, M.

AU - Carta, G.

AU - Meloni, A.

AU - Ghiglieri, V.

AU - Genugu, F.

AU - Puligheddu, M.

AU - Barberini, L.

AU - Marrosu, F.

PY - 2003/7

Y1 - 2003/7

N2 - DBA/2J mice present spontaneous spiking activity resembling the petit-mal in humans and mainly dependant by GABAB receptors. The present study address the digital EEG analysis of the spike composition versus the seizure activity induced or reduced by agonists and antagonists respectively. Moreover, the profile of Levetiracetam (LEV), a new anticonvulsant, has been described accordingly. A further and correlated analysis investigate the modifications of the EEG background in the above conditions using an original algorhythm.

AB - DBA/2J mice present spontaneous spiking activity resembling the petit-mal in humans and mainly dependant by GABAB receptors. The present study address the digital EEG analysis of the spike composition versus the seizure activity induced or reduced by agonists and antagonists respectively. Moreover, the profile of Levetiracetam (LEV), a new anticonvulsant, has been described accordingly. A further and correlated analysis investigate the modifications of the EEG background in the above conditions using an original algorhythm.

KW - Baclofen

KW - DBA2J Mice

KW - Digital EEG

KW - Levetiracetam

KW - SCH 50911

UR - http://www.scopus.com/inward/record.url?scp=10744224545&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=10744224545&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:10744224545

SP - 317

EP - 319

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

SN - 0394-560X

IS - 121-122

ER -

Modificazione del segnale EEG nei topi DBA/2J dopo trattamento agonistico e antagonistico dei recettori GABAB

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this