Modificazione del segnale EEG nei topi DBA/2J dopo trattamento agonistico e antagonistico dei recettori GABAB

Translated title of the contribution: EEG variations following GABAB agonist and antagonist treatment in DBA/2J mice

F. Santoni, G. P. Mereu, M. Fà, G. Carta, A. Meloni, V. Ghiglieri, F. Genugu, M. Puligheddu, L. Barberini, F. Marrosu

Research output: Contribution to journalArticlepeer-review

Abstract

DBA/2J mice present spontaneous spiking activity resembling the petit-mal in humans and mainly dependant by GABAB receptors. The present study address the digital EEG analysis of the spike composition versus the seizure activity induced or reduced by agonists and antagonists respectively. Moreover, the profile of Levetiracetam (LEV), a new anticonvulsant, has been described accordingly. A further and correlated analysis investigate the modifications of the EEG background in the above conditions using an original algorhythm.

Translated title of the contributionEEG variations following GABAB agonist and antagonist treatment in DBA/2J mice
Original languageItalian
Pages (from-to)317-319
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number121-122
Publication statusPublished - Jul 2003

ASJC Scopus subject areas

  • Clinical Neurology

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