Abstract
3, 5 Dimethylpyrazole lowers plasma free fatty acids in fed and fasted rats as well as in rats exposed to cold, submitted to adrenalectomy or treated with noradrenaline, ACTH or chlorpromazine. The accumulation of liver triglycerides following cold exposure, ethanol administration or ACTH treatment is also inhibited by 3, 5 dimethylpyrazole. In contrast with the marked effect on lipid metabolism, 3, 5 dimethylpyrazole did not exhibit any major effect on normal level of blood glucose or on hyperglycemia induced by glucose load or chlorpromazine treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 1371-1375 |
| Number of pages | 5 |
| Journal | Life Sciences |
| Volume | 3 |
| Issue number | 12 |
| Publication status | Published - Dec 1964 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmacology
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Effect of 3, 5 dimethylpyrazole on blood free fatty acids and glucose. / Rizzi, A.; Jori, A.; Veneroni, E.; Garattini, S.
In: Life Sciences, Vol. 3, No. 12, 12.1964, p. 1371-1375.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of 3, 5 dimethylpyrazole on blood free fatty acids and glucose
AU - Rizzi, A.
AU - Jori, A.
AU - Veneroni, E.
AU - Garattini, S.
PY - 1964/12
Y1 - 1964/12
N2 - 3, 5 Dimethylpyrazole lowers plasma free fatty acids in fed and fasted rats as well as in rats exposed to cold, submitted to adrenalectomy or treated with noradrenaline, ACTH or chlorpromazine. The accumulation of liver triglycerides following cold exposure, ethanol administration or ACTH treatment is also inhibited by 3, 5 dimethylpyrazole. In contrast with the marked effect on lipid metabolism, 3, 5 dimethylpyrazole did not exhibit any major effect on normal level of blood glucose or on hyperglycemia induced by glucose load or chlorpromazine treatment.
AB - 3, 5 Dimethylpyrazole lowers plasma free fatty acids in fed and fasted rats as well as in rats exposed to cold, submitted to adrenalectomy or treated with noradrenaline, ACTH or chlorpromazine. The accumulation of liver triglycerides following cold exposure, ethanol administration or ACTH treatment is also inhibited by 3, 5 dimethylpyrazole. In contrast with the marked effect on lipid metabolism, 3, 5 dimethylpyrazole did not exhibit any major effect on normal level of blood glucose or on hyperglycemia induced by glucose load or chlorpromazine treatment.
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UR - http://www.scopus.com/inward/citedby.url?scp=34447635784&partnerID=8YFLogxK
M3 - Article
C2 - 14248624
AN - SCOPUS:34447635784
VL - 3
SP - 1371
EP - 1375
JO - Life Sciences
JF - Life Sciences
SN - 0024-3205
IS - 12
ER -