Effect of 3, 5 dimethylpyrazole on blood free fatty acids and glucose

A. Rizzi, A. Jori, E. Veneroni, S. Garattini

Research output: Contribution to journalArticle

Abstract

3, 5 Dimethylpyrazole lowers plasma free fatty acids in fed and fasted rats as well as in rats exposed to cold, submitted to adrenalectomy or treated with noradrenaline, ACTH or chlorpromazine. The accumulation of liver triglycerides following cold exposure, ethanol administration or ACTH treatment is also inhibited by 3, 5 dimethylpyrazole. In contrast with the marked effect on lipid metabolism, 3, 5 dimethylpyrazole did not exhibit any major effect on normal level of blood glucose or on hyperglycemia induced by glucose load or chlorpromazine treatment.

Original languageEnglish
Pages (from-to)1371-1375
Number of pages5
JournalLife Sciences
Volume3
Issue number12
Publication statusPublished - Dec 1964

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Nonesterified Fatty Acids
Blood
Chlorpromazine
Glucose
Adrenocorticotropic Hormone
Rats
Adrenalectomy
Lipid Metabolism
Hyperglycemia
Liver
Blood Glucose
Norepinephrine
Triglycerides
Ethanol
Plasmas
3,5-dimethylpyrazole

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology

Cite this

Effect of 3, 5 dimethylpyrazole on blood free fatty acids and glucose. / Rizzi, A.; Jori, A.; Veneroni, E.; Garattini, S.

In: Life Sciences, Vol. 3, No. 12, 12.1964, p. 1371-1375.

Research output: Contribution to journalArticle

Rizzi, A, Jori, A, Veneroni, E & Garattini, S 1964, 'Effect of 3, 5 dimethylpyrazole on blood free fatty acids and glucose', Life Sciences, vol. 3, no. 12, pp. 1371-1375.
Rizzi, A. ; Jori, A. ; Veneroni, E. ; Garattini, S. / Effect of 3, 5 dimethylpyrazole on blood free fatty acids and glucose. In: Life Sciences. 1964 ; Vol. 3, No. 12. pp. 1371-1375.
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