Effect of abciximab on prothrombin activation and thrombin generation in patients with acute myocardial infarction also receiving reteplase

Piera Angelica Merlini, Alessandra Repetto, Anna Maria Andreoli, Silvio Ricci, Alessandro Lombardi, Angelo Finardi, Giuseppe Dipasquale, Monica Lamponi, Pier Mannuccio Mannucci, Diego Ardissino

Research output: Contribution to journalArticlepeer-review

Abstract

Fibrinolysis in acute myocardial infarction activates blood coagulation and may favor reocclusion or ischemic complications. The aim of the GUSTO V Italian Hematologic Substudy was to compare the effects of full-dose reteplase on coagulation activation markers with those of half-dose reteplase combined with full-dose abciximab, a platelet glycoprotein IIb/IIIa receptor antagonist, during the early phase after acute myocardial infarction.

Original languageEnglish
Pages (from-to)195-198
Number of pages4
JournalThe American Journal of Cardiology
Volume93
Issue number2
DOIs
Publication statusPublished - Jan 15 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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