Effect of acetabular cup design on metal ion release in two designs of metal-on-metal hip resurfacing

Matteo Cadossi, Giuseppe Tedesco, Lucia Savarino, Nicola Baldini, Antonio Mazzotti, Michelina Greco, Sandro Giannini

Research output: Contribution to journalArticlepeer-review


The purpose of this observational prospective cohort study was to evaluate the serum concentrations of cobalt (Co), chromium (Cr), and nickel (Ni) at a 2-year followup in patients operated on with a novel design of hip resurfacing: Romax resurfacing system (RRS). RRS is characterized by the presence of an acetabular notch which theoretically provides a wider range of motion and a reduced incidence of groin pain. The presence of radiolucencies and functional outcome, assessed using the Harris hip score (HHS) and the University of California Activity scale (UCLA), were secondary endpoints. Moreover, these results were compared with those obtained in our previous study from a similar cohort of patients implanted using the Birmingham Hip Resurfacing (BHR) system. At a 2-year follow-up, the serum levels of Co in patients operated on using the RRS were five times higher (p50.0002) than those found before surgery (Co, means: 1.04 and 0.20 ng/mL, respectively); similarly, Cr levels were 13 times higher (p

Original languageEnglish
Pages (from-to)1595-1601
Number of pages7
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Issue number7
Publication statusPublished - Oct 1 2014


  • Acetabular notch
  • Hip resurfacing
  • Metal ions
  • Metal-on-metal
  • Prosthesis

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Medicine(all)


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