Abstract
We studied the effects of acetyl-L-carnitine on pain in 16 HIV+ patients affected by painful distal symmetrical neuropathy. Patients were treated with 0.5-1 gr per day of acetyl-L-carnitine either i.m. or i.v. for 3 weeks. Pain intensity was measured before and after the treatment by the Huskisson's analogic scale. Ten patients (62.5%) reported an improvement of symptoms, five patients (31.25%) were unchanged, one patient worsened. The results of this open study show that acetyl-L-carnitine can have a role in the treatment of pain in distal symmetrical polyneuropathy related to HIV infection. However, further double-blind, placebo-controlled studies are needed to confirm these preliminary results.
| Original language | English |
|---|---|
| Pages (from-to) | 250-252 |
| Number of pages | 3 |
| Journal | Journal of the Peripheral Nervous System |
| Volume | 2 |
| Issue number | 3 |
| Publication status | Published - 1997 |
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Keywords
- Acetyl-L-carnitine
- AIDS
- Chronic pain
- HIV+ neuropathy
- Painful distal symmetrical polyneuropathy
- Peripheral neuropathy
- Therapy of peripheral neuropathies
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Effect of acetyl-L-carnitine in the treatment of painful peripheral neuropathies in HIV+ patients. / Scarpini, Elio; Sacilotto, Giorgio; Baron, Pierluigi; Cusini, Marco; Scarlato, Guglielmo.
In: Journal of the Peripheral Nervous System, Vol. 2, No. 3, 1997, p. 250-252.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of acetyl-L-carnitine in the treatment of painful peripheral neuropathies in HIV+ patients
AU - Scarpini, Elio
AU - Sacilotto, Giorgio
AU - Baron, Pierluigi
AU - Cusini, Marco
AU - Scarlato, Guglielmo
PY - 1997
Y1 - 1997
N2 - We studied the effects of acetyl-L-carnitine on pain in 16 HIV+ patients affected by painful distal symmetrical neuropathy. Patients were treated with 0.5-1 gr per day of acetyl-L-carnitine either i.m. or i.v. for 3 weeks. Pain intensity was measured before and after the treatment by the Huskisson's analogic scale. Ten patients (62.5%) reported an improvement of symptoms, five patients (31.25%) were unchanged, one patient worsened. The results of this open study show that acetyl-L-carnitine can have a role in the treatment of pain in distal symmetrical polyneuropathy related to HIV infection. However, further double-blind, placebo-controlled studies are needed to confirm these preliminary results.
AB - We studied the effects of acetyl-L-carnitine on pain in 16 HIV+ patients affected by painful distal symmetrical neuropathy. Patients were treated with 0.5-1 gr per day of acetyl-L-carnitine either i.m. or i.v. for 3 weeks. Pain intensity was measured before and after the treatment by the Huskisson's analogic scale. Ten patients (62.5%) reported an improvement of symptoms, five patients (31.25%) were unchanged, one patient worsened. The results of this open study show that acetyl-L-carnitine can have a role in the treatment of pain in distal symmetrical polyneuropathy related to HIV infection. However, further double-blind, placebo-controlled studies are needed to confirm these preliminary results.
KW - Acetyl-L-carnitine
KW - AIDS
KW - Chronic pain
KW - HIV+ neuropathy
KW - Painful distal symmetrical polyneuropathy
KW - Peripheral neuropathy
KW - Therapy of peripheral neuropathies
UR - http://www.scopus.com/inward/record.url?scp=0031290516&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031290516&partnerID=8YFLogxK
M3 - Article
C2 - 10975731
AN - SCOPUS:0031290516
VL - 2
SP - 250
EP - 252
JO - Journal of the Peripheral Nervous System
JF - Journal of the Peripheral Nervous System
SN - 1085-9489
IS - 3
ER -