Effect of an antidopaminergic drug on LH, FSH and PRL levels in post-menopausal women

Natural or synthetic estrogens are the most common treatment of menopausal syndrome. One of the most unpleasant symptoms is vasomotor instability which results in characteristic 'hot flushes'. Catecholamines seem to play a role in producing this symptom. Veralipride is a new benzamine derivative, which showed a central antidopaminergic effect. We studied this drug in the treatment of the menopausal syndrome, because there is more evidence of neuroendocrinologic factor, related to changes in catecholamines in 'hot flushes'.