Effect of antiepileptic drugs on sleep

Fabio Placidi, Anna Scalise, Maria Grazia Marciani, Andrea Romigi, Marina Diomedi, Gian Luigi Gigli

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

The interactions between sleep and epilepsy are well known. A nodal point of the relationship between sleep and epilepsy is represented by pharmacological treatment. Sleep disturbances such as drowsiness are among the most frequent side effects of treatment with antiepileptic drugs, since they can deeply modify both sleep architecture and the sleep-wake cycle. Severe daytime somnolence affects patients' activities and it may facilitate the occurrence of seizures. These considerations underline the importance of antiepileptic drugs having anticonvulsant properties that do not negatively influence sleep and daytime somnolence. In this paper we review some relevant aspects of the effects of antiepileptic drugs on sleep. (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
JournalClinical Neurophysiology
Volume111
Issue numberSUPPL. 2
DOIs
Publication statusPublished - Sep 1 2000

Fingerprint

Anticonvulsants
Sleep
Epilepsy
Sleep Stages
Seizures
Pharmacology
Therapeutics

Keywords

  • Antiepileptic drugs
  • Epilepsy
  • Polysomnography
  • Sleep

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems

Cite this

Placidi, F., Scalise, A., Marciani, M. G., Romigi, A., Diomedi, M., & Gigli, G. L. (2000). Effect of antiepileptic drugs on sleep. Clinical Neurophysiology, 111(SUPPL. 2). https://doi.org/10.1016/S1388-2457(00)00411-9

Effect of antiepileptic drugs on sleep. / Placidi, Fabio; Scalise, Anna; Marciani, Maria Grazia; Romigi, Andrea; Diomedi, Marina; Gigli, Gian Luigi.

In: Clinical Neurophysiology, Vol. 111, No. SUPPL. 2, 01.09.2000.

Research output: Contribution to journalArticle

Placidi, F, Scalise, A, Marciani, MG, Romigi, A, Diomedi, M & Gigli, GL 2000, 'Effect of antiepileptic drugs on sleep', Clinical Neurophysiology, vol. 111, no. SUPPL. 2. https://doi.org/10.1016/S1388-2457(00)00411-9
Placidi F, Scalise A, Marciani MG, Romigi A, Diomedi M, Gigli GL. Effect of antiepileptic drugs on sleep. Clinical Neurophysiology. 2000 Sep 1;111(SUPPL. 2). https://doi.org/10.1016/S1388-2457(00)00411-9
Placidi, Fabio ; Scalise, Anna ; Marciani, Maria Grazia ; Romigi, Andrea ; Diomedi, Marina ; Gigli, Gian Luigi. / Effect of antiepileptic drugs on sleep. In: Clinical Neurophysiology. 2000 ; Vol. 111, No. SUPPL. 2.
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