Effect of ccl4 intoxication on the synthesis of β-lipoprotein fractions in rat liver

O. Albano, A. Francavilla

Research output: Contribution to journalArticlepeer-review

Abstract

The incorporation of [14C]leucine and [3H]palmitic acid into the β-lipoproteins of liver and plasma of normal and CCl4-intoxicated rats has been studied. It has been found that CCl4, inhibits the incorporation of [14C]leucine and [3H]palmitic acid into β-lipoproteins isolated from the liver and the plasma and causes an increase in the 3H/14C ratio. The very low density and the low-density lipoprotein fractions were also isolated from rat liver cellular sap. Inhibition of incorporation of both substances is much more marked at the expense of the very low density fraction.

Original languageEnglish
Pages (from-to)363-366
Number of pages4
JournalClinica Chimica Acta
Volume19
Issue number3
Publication statusPublished - Mar 1968

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry

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