Effect of chronic lead treatment on brain dopamine synthesis and serum prolactin release in the rat

S. Govoni, O. Montefusco, P. F. Spano, M. Trabucchi

Research output: Contribution to journalArticle

Abstract

The effect of chronic dietary lead exposure on brain striata dopaminergic transmission was studied in rats by measuring dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) levels. Serum prolactin (PRL) concentration was also measured. The results show a decreased striatal dopamine synthesis and increased serum PRL concentrations.

Original languageEnglish
Pages (from-to)333-337
Number of pages5
JournalToxicology Letters
Volume2
Issue number6
DOIs
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Toxicology

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