Effect of coffee on exercise-induced angina pectoris due to coronary artery disease in habitual coffee drinkers

Kenneth M. Piters, Antonio Colombo, Harold G. Olson, Samuel M. Butman

Research output: Contribution to journalArticlepeer-review

Abstract

The acute effects of coffee on exercise-induced angina were studied in 17 men with coronary artery disease using a double-blind treadmill protocol. Ingestion of either 1 or 2 cups of caffeinated coffee increased the exercise duration until onset of angina (8 and 12%, respectively, p <0.05), whereas decaffeinated coffee had no effect. The extent of ST-segment depression and the heart rate-blood pressure product at angina were similar after drinking caffeinated and decaffeinated coffee. Exercise duration until 0.1 mV of ST-segment depression, as well as the heart rate, blood pressure and double product at angina and at 0.1 mV of ST-segment depression were similar after drinking caffeinated or decaffeinated coffee. The mean serum caffeine levels (± standard deviation) after ingestion of 1 and 2 cups of caffeinated coffee were 1.97 ± 1.0 and 3.89 ± 1.6 μg/ml, respectively. The acute ingestion of 1 to 2 cups of caffeinated coffee had no deleterious effect on exercise-induced angina pectoris in patients with coronary artery disease.

Original languageEnglish
Pages (from-to)277-280
Number of pages4
JournalThe American Journal of Cardiology
Volume55
Issue number4
DOIs
Publication statusPublished - Feb 1 1985

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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