Effect of colchicine and vinblastine on identified leech neurons

Mario Pellegrino, Michela Matteoli, Laura Bertolacci

Research output: Contribution to journalArticlepeer-review


1. An identified neuron of the leech central nervous system is affected by the application of colchicine or vinblastine to its axon. 2. It develops characteristic changes of membrane electrical properties, which are similar to those observed after surgical axotomy. 3. The ionic mechanisms associated with the impulses induced by axotomy and colchicine treatment are not equivalent.

Original languageEnglish
Pages (from-to)353-356
Number of pages4
JournalComparative Biochemistry and Physiology. Part C, Comparative
Issue number2
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Immunology
  • Pharmacology


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