Effect of colchicine and vinblastine on identified leech neurons

Mario Pellegrino; Michela Matteoli; Laura Bertolacci

doi:10.1016/0742-8413(85)90175-6

Effect of colchicine and vinblastine on identified leech neurons

Mario Pellegrino, Michela Matteoli, Laura Bertolacci

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

1. An identified neuron of the leech central nervous system is affected by the application of colchicine or vinblastine to its axon. 2. It develops characteristic changes of membrane electrical properties, which are similar to those observed after surgical axotomy. 3. The ionic mechanisms associated with the impulses induced by axotomy and colchicine treatment are not equivalent.

Original language	English
Pages (from-to)	353-356
Number of pages	4
Journal	Comparative Biochemistry and Physiology. Part C, Comparative
Volume	82
Issue number	2
DOIs	https://doi.org/10.1016/0742-8413(85)90175-6
Publication status	Published - 1985

ASJC Scopus subject areas

Immunology
Pharmacology

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abstract = "1. An identified neuron of the leech central nervous system is affected by the application of colchicine or vinblastine to its axon. 2. It develops characteristic changes of membrane electrical properties, which are similar to those observed after surgical axotomy. 3. The ionic mechanisms associated with the impulses induced by axotomy and colchicine treatment are not equivalent.",

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