Effect of detraining on the cardiopulmonary reflex in professional runners and hammer throwers

Cristina Giannattasio, Gino Seravalle, Bianca M. Cattaneo, Cesare Cuspidi, Lorena Sampieri, Gianni B. Bolla, Guido Grassi, Giuseppe Mancia

Research output: Contribution to journalArticle

Abstract

In professional athletes with marked cardiac hypertrophy, reflex influences originating from cardiopulmonary receptors are impaired. To determine whether the reflex is restored after termination of physical training and regression of cardiac hypertrophy 8 former athletes (age 31 ± 6 years, mean ± SD) who stopped agonistic activity for 5 ±1 years were compared with 15 sedentary subjects (27 ± 7 years) and 19 active professional athletes (22 ± 7 years). Cardiopulmonary receptor stimulation and deactivation were obtained by increasing and reducing left ventricular end-diastolic diameter (echocardiography) through leg raising and nonhypotensive lower body negative pressure, respectively. Left ventricular mass index (echocardiography) was markedly and significantly (p <0.01) greater in athletes (135 ± 6 g/m2) than in former athletes (105 ± 4 g/m2) whose value was similar to that of sedentary subjects (98 ± 4 g/m2). The reduction in forearm vascular resistance and plasma norepinephrine induced by increasing left ventricular end-diastolic diameter was 24 and 23% less in athletes than in former athletes whose responses were similar to those of sedentary subjects. This was the case also for the responses induced by reducing left ventricular end-diastolic diameter. In contrast, the hemodynamic responses to cold presser test were similar in the 3 groups. It is concluded that the impairment of the cardiopulmonary reflex observed in athletes is largely reversible when physical training is terminated. This may be due to regression of left ventricular hypertrophy.

Original languageEnglish
Pages (from-to)677-680
Number of pages4
JournalThe American Journal of Cardiology
Volume69
Issue number6
DOIs
Publication statusPublished - Mar 1 1992

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Athletes
Reflex
Cardiomegaly
Echocardiography
Lower Body Negative Pressure
Left Ventricular Hypertrophy
Forearm
Vascular Resistance
Leg
Norepinephrine
Hemodynamics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Effect of detraining on the cardiopulmonary reflex in professional runners and hammer throwers. / Giannattasio, Cristina; Seravalle, Gino; Cattaneo, Bianca M.; Cuspidi, Cesare; Sampieri, Lorena; Bolla, Gianni B.; Grassi, Guido; Mancia, Giuseppe.

In: The American Journal of Cardiology, Vol. 69, No. 6, 01.03.1992, p. 677-680.

Research output: Contribution to journalArticle

Giannattasio, Cristina ; Seravalle, Gino ; Cattaneo, Bianca M. ; Cuspidi, Cesare ; Sampieri, Lorena ; Bolla, Gianni B. ; Grassi, Guido ; Mancia, Giuseppe. / Effect of detraining on the cardiopulmonary reflex in professional runners and hammer throwers. In: The American Journal of Cardiology. 1992 ; Vol. 69, No. 6. pp. 677-680.
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