Effect of different interventions on heart rate variability after heart transplantation: Non-autonomic vs autonomic factors

L. Bernardi, S. Leuzzi, F. Valle, L. Martinelli, C. Passino, M. Rinaldi, G. Spadacini, M. Vigano, G. Finardi, P. Sleight

Research output: Contribution to journalArticlepeer-review

Abstract

1. The human transplanted heart is initially denervated, hence any fluctuation present in the RR interval variability can be either due to reaquired innervation, or to the effect of some non autonomic activity, such as a direct effect of respiration on atrial (sinus node) stretch. 2. In order to distinguish between sympathetic, vagal and non autonomic factors we examined the effects of various physical and pharmacologic manoeuvres on the respiratory and non-respiratory components of heart rate variability. 3. We found that sinusoidal neck suction appears a useful, noninvasive tool to characterise the relative importance of the different factors, which can influence heart rate variability in the transplanted heart.

Original languageEnglish
Pages (from-to)22-24
Number of pages3
JournalClinical Science
Volume91
Issue number1 SUPPL.
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Medicine(all)

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