Effect of dihydroergocristine on prolactin release from isolated and dispersed rat pituitary cells

R. D'Urso, P. Falaschi, R. Jellamo, S. Ruggieri

Research output: Contribution to journalArticle

Abstract

Dihydroergocristine, an ergot alkaloid derivative, has an inhibitory effect on prolactine (PRL) release in man. In order to investigate whether the responses obtained are due to a direct effect on the pituitary or are mediated through extrapituitary mechanisms, we studied the effect of the drug on PRL release in a system of isolated and dispersed rat pituitary cells. The reduction of PRL release obtained in this test system is due to a direct effect.

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalActa Therapeutica
Volume8
Issue number2
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Medicine(all)

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