Administration of dihydroxydibutylether (DHBE, Dis-Cinil) to rats with ethynlestradiol(EE)-induced cholestasis provokes an increase in bile flow and output of bile acids and phospholipids. Since EE-induced cholestasis is related to the condition observed in humans, a clinical trial of DHRE in cholestatic syndromes seems worthwhile.
|Number of pages||3|
|Publication status||Published - 1980|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry