Effect of ileal infusion of glycochenodeoxycholic acid on segmental transit, motility, and flow in the human jejunum and ileum

R. Penagini, R. C. Spiller, J. J. Misiewicz, P. G. Frost

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The hypothesis that the presence of glycochenodeoxycholic acid (GCDC) in the human Heal bile acid concentrations showed a 54·0 (9·3)% absorption of glycochenodeoxycholic acid by the been tested in healthy volunteers. Mean transit times, flow rates and intraluminal pressures in a 40 cm jejunal segment proximal (n=6) and a 40 cm ileal segment distal (n=6) to a GCDC infusion port were measured. During GCDC infusion (60 μmol/min) jejunal and ileal transit were markedly (p

Original languageEnglish
Pages (from-to)609-617
Number of pages9
JournalGut
Volume30
Issue number5
Publication statusPublished - May 1989

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Glycochenodeoxycholic Acid
Jejunum
Ileum
Bile Acids and Salts
Healthy Volunteers
Pressure

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Effect of ileal infusion of glycochenodeoxycholic acid on segmental transit, motility, and flow in the human jejunum and ileum. / Penagini, R.; Spiller, R. C.; Misiewicz, J. J.; Frost, P. G.

In: Gut, Vol. 30, No. 5, 05.1989, p. 609-617.

Research output: Contribution to journalArticle

Penagini, R. ; Spiller, R. C. ; Misiewicz, J. J. ; Frost, P. G. / Effect of ileal infusion of glycochenodeoxycholic acid on segmental transit, motility, and flow in the human jejunum and ileum. In: Gut. 1989 ; Vol. 30, No. 5. pp. 609-617.
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