TY - JOUR
T1 - Effect of immersion in CO2-enriched water on free radical release and total antioxidant status in peripheral arterial occlusive disease
AU - Dogliotti, G.
AU - Galliera, E.
AU - Iorio, E.
AU - De Bernardi Di Valserra, M.
AU - Solimene, U.
AU - Corsi, M. M.
PY - 2011/2
Y1 - 2011/2
N2 - Aim. The aim of this paper was to investigate the release of oxygen free radicals in patients with peripheral occlusive arterial disease and the effects of immersion of the legs and feet in carbon dioxide (CO2)-enriched water. Methods. Twenty-five patients with peripheral occlusive arterial disease (Fontaine stage II) and 15 healthy controls were treated by immersing the lower legs in either CO2-enriched or normal spa water. Blood samples were collected in heparinized tubes and total antioxidant status (TAS) and reactive oxygen metabolites (ROMs) were measured after five treatments a week for two weeks. Results. d-ROM plasma levels decreased in patients with peripheral occlusive disease after immersion in CO2.enriched water (P2-enriched water immersion had a positive effect, reducing free radical plasma levels and raising the levels of antioxidants, suggesting an improvement in the microcirculation.
AB - Aim. The aim of this paper was to investigate the release of oxygen free radicals in patients with peripheral occlusive arterial disease and the effects of immersion of the legs and feet in carbon dioxide (CO2)-enriched water. Methods. Twenty-five patients with peripheral occlusive arterial disease (Fontaine stage II) and 15 healthy controls were treated by immersing the lower legs in either CO2-enriched or normal spa water. Blood samples were collected in heparinized tubes and total antioxidant status (TAS) and reactive oxygen metabolites (ROMs) were measured after five treatments a week for two weeks. Results. d-ROM plasma levels decreased in patients with peripheral occlusive disease after immersion in CO2.enriched water (P2-enriched water immersion had a positive effect, reducing free radical plasma levels and raising the levels of antioxidants, suggesting an improvement in the microcirculation.
KW - Arterial occlusive diseases
KW - Free radicals
KW - Reactive oxygen species
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M3 - Article
C2 - 21248668
AN - SCOPUS:79955368679
VL - 30
SP - 12
EP - 17
JO - International Angiology
JF - International Angiology
SN - 0392-9590
IS - 1
ER -