Effect of insulin treatment on osteocalcin levels in diabetic children and adolescents

M. P. Guarneri, Giovanna Weber, P. Gallia, G. Chiumello

Research output: Contribution to journalArticle

Abstract

To investigate bone mineral metabolism in insulin-dependent diabetes mellitus, serum osteocalcin, a marker of bone formation, was measured in 31 diabetic children at onset of disease and 15 days after metabolic improvement by insulin therapy. As a control group for osteocalcin levels we studied 31 healthy sex- and age-matched children. Mean values of serum osteocalcin at onset of diabetes were significantly lower than in control group (p

Original languageEnglish
Pages (from-to)505-509
Number of pages5
JournalJournal of Endocrinological Investigation
Volume16
Issue number7
DOIs
Publication statusPublished - 1993

Keywords

  • adolescents
  • children
  • insulin-dependent diabetes mellitus
  • Osteocalcin
  • osteopenia
  • parathyroid hormone

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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