Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence

M. Petti; S. Caschera; A. Anzolin; J. Toppi; F. Pichiorri; F. Babiloni; F. Cincotti; D. Mattia; L. Astolfi

doi:10.1109/EMBC.2015.7319219

Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence

M. Petti, S. Caschera, A. Anzolin, J. Toppi, F. Pichiorri, F. Babiloni, F. Cincotti, D. Mattia, L. Astolfi

Fondazione Santa Lucia

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Partial Directed Coherence (PDC) is a powerful estimator of effective connectivity. In neuroscience it is used in different applications with the aim to investigate the communication between brain regions during the execution of different motor or cognitive tasks. When multiple trials are available, PDC can be computed over multiple realizations, provided that the assumption of stationarity across trials is verified. This allows to improve the amount of data, which is an important constraint for the estimation accuracy. However, the stationarity of the data across trials is not always guaranteed, especially when dealing with patients. In this study we investigated how the inter-trials variability of an EEG dataset affects the PDC accuracy. Effects of density variations and of changes of connectivity values across trials were first investigated with a simulation study and then tested on real EEG data collected from two post-stroke patients during a motor imagery task and characterized by different inter-trials variability. Results showed the effect of different factors on the PDC accuracy and the robustness of such estimator in a range of conditions met in practical applications.

Original language	English
Title of host publication	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	3791-3794
Number of pages	4
Volume	2015-November
ISBN (Print)	9781424492718
DOIs	https://doi.org/10.1109/EMBC.2015.7319219
Publication status	Published - Nov 4 2015
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: Aug 25 2015 → Aug 29 2015

Other

Other	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country	Italy
City	Milan
Period	8/25/15 → 8/29/15

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

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Petti, M., Caschera, S., Anzolin, A., Toppi, J., Pichiorri, F., Babiloni, F., Cincotti, F., Mattia, D., & Astolfi, L. (2015). Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (Vol. 2015-November, pp. 3791-3794). [7319219] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7319219

Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence. / Petti, M.; Caschera, S.; Anzolin, A.; Toppi, J.; Pichiorri, F.; Babiloni, F.; Cincotti, F.; Mattia, D.; Astolfi, L.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 3791-3794 7319219.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Petti, M, Caschera, S, Anzolin, A, Toppi, J, Pichiorri, F, Babiloni, F, Cincotti, F , Mattia, D & Astolfi, L 2015, Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7319219, Institute of Electrical and Electronics Engineers Inc., pp. 3791-3794, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. https://doi.org/10.1109/EMBC.2015.7319219

Petti M, Caschera S, Anzolin A, Toppi J, Pichiorri F, Babiloni F et al. Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November. Institute of Electrical and Electronics Engineers Inc. 2015. p. 3791-3794. 7319219 https://doi.org/10.1109/EMBC.2015.7319219

Petti, M. ; Caschera, S. ; Anzolin, A. ; Toppi, J. ; Pichiorri, F. ; Babiloni, F. ; Cincotti, F. ; Mattia, D. ; Astolfi, L. / Effect of inter-trials variability on the estimation of cortical connectivity by Partial Directed Coherence. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. pp. 3791-3794

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