Effect of metergoline, a specific serotonin antagonist, on human growth hormone response to arginine and L Dopa

A. E. Pontiroli, G. C. Viberti, A. Tognetti, G. Pozza

Research output: Contribution to journalArticlepeer-review

Abstract

In seven normal subjects the repeated oral administration of metergoline, a specific antiserotonin agent, has enhanced HGH response to arginine infusion. Following placebo administration, arginine induced HGH release was slightly but not significantly reduced; similarly, in eight metergoline treated subjects, HGH response to oral L Dopa was slightly but not significantly reduced. HGH response to i.v. L Dopa was not modified by the drug. These results suggest that serotonin controls HGH response only in response to arginine, not to L Dopa.

Original languageEnglish
Pages (from-to)106-108
Number of pages3
JournalHormone and Metabolic Research
Volume8
Issue number2
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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