Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease

F. Girotti; F. Carella; G. Scigliano; M. P. Grassi; P. Soliveri; P. Giovannini; E. Parati; T. Caraceni

doi:10.1136/jnnp.47.8.848

Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease

F. Girotti, F. Carella, G. Scigliano, M. P. Grassi, P. Soliveri, P. Giovannini, E. Parati, T. Caraceni

Fondazione IRCCS Istituto Neurologico "C. Besta"

Research output: Contribution to journal › Article › peer-review

Abstract

Eighteen patients with Huntington's chorea were examined before and after neuroleptic treatment (haloperidol, pimozide, tiapride) to study the effect of such treatment on hyperkinesia and motor performance. Pimozide and haloperidol improved hyperkinesia; none of the drugs significantly affected motor performance. No correlation was found between the severity of hyperkinesia and motor performance scores, or between hyperkinesia and intelligence score, before and after therapy.

Original language	English
Pages (from-to)	848-852
Number of pages	5
Journal	Journal of Neurology, Neurosurgery and Psychiatry
Volume	47
Issue number	8
DOIs	https://doi.org/10.1136/jnnp.47.8.848
Publication status	Published - 1984

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Neuropsychology and Physiological Psychology
Neuroscience(all)
Psychiatry and Mental health

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10.1136/jnnp.47.8.848

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Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease. / Girotti, F.; Carella, F.; Scigliano, G.; Grassi, M. P.; Soliveri, P.; Giovannini, P.; Parati, E.; Caraceni, T.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 47, No. 8, 1984, p. 848-852.

Research output: Contribution to journal › Article › peer-review

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AU - Giovannini, P.

AU - Parati, E.

AU - Caraceni, T.

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Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease

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