Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease

F. Girotti, F. Carella, G. Scigliano, M. P. Grassi, P. Soliveri, P. Giovannini, E. Parati, T. Caraceni

Research output: Contribution to journalArticlepeer-review

Abstract

Eighteen patients with Huntington's chorea were examined before and after neuroleptic treatment (haloperidol, pimozide, tiapride) to study the effect of such treatment on hyperkinesia and motor performance. Pimozide and haloperidol improved hyperkinesia; none of the drugs significantly affected motor performance. No correlation was found between the severity of hyperkinesia and motor performance scores, or between hyperkinesia and intelligence score, before and after therapy.

Original languageEnglish
Pages (from-to)848-852
Number of pages5
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume47
Issue number8
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

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