Effect of non-sucrose sweet tasting solution on neonatal heel prick responses

Luca A. Ramenghi, Gillian C. Griffith, Christopher M. Wood, Malcolm I. Levene

Research output: Contribution to journalArticle


A substance commercially described as 'sugar free,' used as a sweetener for paracetamol suspension, was evaluated on measures of neonatal pain. Sixty infants were randomly allocated to receive one of four solutions before heel stab blood sampling: sterile water (placebo); 25 or 50% sucrose (weight/volume); and the commercial sweet-tasting solution. There was a significant reduction in crying time and pain score 3 minutes after the painful stimulus in all groups compared with the controls. It is concluded that this sweet-tasting solution has analgesic effects as potent as those of concentrated sucrose solutions.

Original languageEnglish
JournalArchives of Disease in Childhood
Issue number2 SUPPL.
Publication statusPublished - Mar 1996


  • Analgesia
  • Behavioural response
  • Heel prick
  • Sucrose
  • Sweet-tasting solution

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Effect of non-sucrose sweet tasting solution on neonatal heel prick responses'. Together they form a unique fingerprint.

  • Cite this