Effect of perioperative transfusions on survival of osteosarcoma treated by multimodal therapy

R. Chesi, A. Cazzola, G. Bacci, B. Borghi, A. Balladelli, G. Urso

Research output: Contribution to journalArticlepeer-review

Abstract

We report on a retrospective study of 155 patients amputated for nonmetastatic osteosarcoma of the long bones. Among the various prognostic variables considered, a significant correlation was found only between survival and transfusions. In this report, the authors consider some hypotheses reported by others for tumors of a different nature and site and conclude that perioperative transfusion may induce depression in the immune response, which is the cause of a shorter survival in the patients reviewed.

Original languageEnglish
Pages (from-to)1727-1737
Number of pages11
JournalCancer
Volume64
Issue number8
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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