Abstract
Aim. Several studies showed that primary percutaneous coronary interventions (PCI) have a favourable impact on left ventricular remodeling and heart rate variability (HRV) both at short- and long-term follow-up in patients suffering an acute myocardial infarction (AMI). However, no previous study investigated the relationship between left ventricular remodeling and changes in HRV during follow-up in AMI patients treated by primary PCI. Methods. We studied 28 patients with AMI (57±8 years, 27 men), treated by PCI within 12 hours of symptom onset. Patients underwent a 24-hour ECG Holter recording and left ventricular ejection fraction (LVEF) echocardiographic assessment before discharge, and at 1-month and 6-month follow-up. HRV was measured in the time- and frequency-domain. Results. A significant improvement of both time- and frequency-domain HRV variables was observed at 1-month and at 6-month follow-up with the most significant changes being found for standard deviation of normal-normal beat intervals (SDNN) in the time-domain (95.5±26.1 ms vs 125.5±29.8 ms vs 142.8±28.8 ms, respectively; P
| Original language | English |
|---|---|
| Pages (from-to) | 703-710 |
| Number of pages | 8 |
| Journal | Minerva Cardioangiologica |
| Volume | 55 |
| Issue number | 6 |
| Publication status | Published - Dec 2007 |
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Keywords
- Angioplasty, transluminal, percutaneous coronary
- Heart rate
- Myocardial infarction
- Ventricular remodeling
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Effect of primary coronary intervention on heart rate variability and left ventricular function in patients with acute myocardial infarction. / Santangeli, P.; Lamendola, P.; Larosa, C.; Lombardo, A.; Sestito, A.; Infusino, F.; Sgueglia, G. A.; Mariani, L.; Marinaccio, L.; Lanza, G. A.; Crea, F.
In: Minerva Cardioangiologica, Vol. 55, No. 6, 12.2007, p. 703-710.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of primary coronary intervention on heart rate variability and left ventricular function in patients with acute myocardial infarction
AU - Santangeli, P.
AU - Lamendola, P.
AU - Larosa, C.
AU - Lombardo, A.
AU - Sestito, A.
AU - Infusino, F.
AU - Sgueglia, G. A.
AU - Mariani, L.
AU - Marinaccio, L.
AU - Lanza, G. A.
AU - Crea, F.
PY - 2007/12
Y1 - 2007/12
N2 - Aim. Several studies showed that primary percutaneous coronary interventions (PCI) have a favourable impact on left ventricular remodeling and heart rate variability (HRV) both at short- and long-term follow-up in patients suffering an acute myocardial infarction (AMI). However, no previous study investigated the relationship between left ventricular remodeling and changes in HRV during follow-up in AMI patients treated by primary PCI. Methods. We studied 28 patients with AMI (57±8 years, 27 men), treated by PCI within 12 hours of symptom onset. Patients underwent a 24-hour ECG Holter recording and left ventricular ejection fraction (LVEF) echocardiographic assessment before discharge, and at 1-month and 6-month follow-up. HRV was measured in the time- and frequency-domain. Results. A significant improvement of both time- and frequency-domain HRV variables was observed at 1-month and at 6-month follow-up with the most significant changes being found for standard deviation of normal-normal beat intervals (SDNN) in the time-domain (95.5±26.1 ms vs 125.5±29.8 ms vs 142.8±28.8 ms, respectively; P
AB - Aim. Several studies showed that primary percutaneous coronary interventions (PCI) have a favourable impact on left ventricular remodeling and heart rate variability (HRV) both at short- and long-term follow-up in patients suffering an acute myocardial infarction (AMI). However, no previous study investigated the relationship between left ventricular remodeling and changes in HRV during follow-up in AMI patients treated by primary PCI. Methods. We studied 28 patients with AMI (57±8 years, 27 men), treated by PCI within 12 hours of symptom onset. Patients underwent a 24-hour ECG Holter recording and left ventricular ejection fraction (LVEF) echocardiographic assessment before discharge, and at 1-month and 6-month follow-up. HRV was measured in the time- and frequency-domain. Results. A significant improvement of both time- and frequency-domain HRV variables was observed at 1-month and at 6-month follow-up with the most significant changes being found for standard deviation of normal-normal beat intervals (SDNN) in the time-domain (95.5±26.1 ms vs 125.5±29.8 ms vs 142.8±28.8 ms, respectively; P
KW - Angioplasty, transluminal, percutaneous coronary
KW - Heart rate
KW - Myocardial infarction
KW - Ventricular remodeling
UR - http://www.scopus.com/inward/record.url?scp=38649103762&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38649103762&partnerID=8YFLogxK
M3 - Article
VL - 55
SP - 703
EP - 710
JO - Minerva Cardioangiologica
JF - Minerva Cardioangiologica
SN - 0026-4725
IS - 6
ER -