TY - JOUR
T1 - Effect of primary coronary intervention on heart rate variability and left ventricular function in patients with acute myocardial infarction
AU - Santangeli, P.
AU - Lamendola, P.
AU - Larosa, C.
AU - Lombardo, A.
AU - Sestito, A.
AU - Infusino, F.
AU - Sgueglia, G. A.
AU - Mariani, L.
AU - Marinaccio, L.
AU - Lanza, G. A.
AU - Crea, F.
PY - 2007/12
Y1 - 2007/12
N2 - Aim. Several studies showed that primary percutaneous coronary interventions (PCI) have a favourable impact on left ventricular remodeling and heart rate variability (HRV) both at short- and long-term follow-up in patients suffering an acute myocardial infarction (AMI). However, no previous study investigated the relationship between left ventricular remodeling and changes in HRV during follow-up in AMI patients treated by primary PCI. Methods. We studied 28 patients with AMI (57±8 years, 27 men), treated by PCI within 12 hours of symptom onset. Patients underwent a 24-hour ECG Holter recording and left ventricular ejection fraction (LVEF) echocardiographic assessment before discharge, and at 1-month and 6-month follow-up. HRV was measured in the time- and frequency-domain. Results. A significant improvement of both time- and frequency-domain HRV variables was observed at 1-month and at 6-month follow-up with the most significant changes being found for standard deviation of normal-normal beat intervals (SDNN) in the time-domain (95.5±26.1 ms vs 125.5±29.8 ms vs 142.8±28.8 ms, respectively; P
AB - Aim. Several studies showed that primary percutaneous coronary interventions (PCI) have a favourable impact on left ventricular remodeling and heart rate variability (HRV) both at short- and long-term follow-up in patients suffering an acute myocardial infarction (AMI). However, no previous study investigated the relationship between left ventricular remodeling and changes in HRV during follow-up in AMI patients treated by primary PCI. Methods. We studied 28 patients with AMI (57±8 years, 27 men), treated by PCI within 12 hours of symptom onset. Patients underwent a 24-hour ECG Holter recording and left ventricular ejection fraction (LVEF) echocardiographic assessment before discharge, and at 1-month and 6-month follow-up. HRV was measured in the time- and frequency-domain. Results. A significant improvement of both time- and frequency-domain HRV variables was observed at 1-month and at 6-month follow-up with the most significant changes being found for standard deviation of normal-normal beat intervals (SDNN) in the time-domain (95.5±26.1 ms vs 125.5±29.8 ms vs 142.8±28.8 ms, respectively; P
KW - Angioplasty, transluminal, percutaneous coronary
KW - Heart rate
KW - Myocardial infarction
KW - Ventricular remodeling
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M3 - Article
C2 - 18091639
AN - SCOPUS:38649103762
VL - 55
SP - 703
EP - 710
JO - Minerva Cardioangiologica
JF - Minerva Cardioangiologica
SN - 0026-4725
IS - 6
ER -