Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation

F. Bussolino, G. Camussi

Research output: Contribution to journal › Article

17 Citations (Scopus)

Abstract

In this paper, the effect of prostacyclin (PGI2) on the aggregation induced by Platelet-activating factor (PAF), a phospholipid mediator of anaphylaxis, was studied. Synthetic PGI2 and PGI2-like activity generated from rabbit aorta were demonstrated to be effective inhibitors of PAF-induced rabbit platelet aggregation and release of 3H-serotonin (3H-5HT).

Original languageEnglish
Pages (from-to)781-791
Number of pages11
JournalProstaglandins
Volume20
Issue number5
DOIs
Publication statusPublished - 1980

Fingerprint

Platelet Activating Factor
Epoprostenol
Platelets
Platelet Aggregation
Agglomeration
Rabbits
Anaphylaxis
Aorta
Phospholipids
Serotonin

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation. / Bussolino, F.; Camussi, G.

In: Prostaglandins, Vol. 20, No. 5, 1980, p. 781-791.

Research output: Contribution to journal › Article

Bussolino, F & Camussi, G 1980, 'Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation', Prostaglandins, vol. 20, no. 5, pp. 781-791. https://doi.org/10.1016/0090-6980(80)90133-1
Bussolino F, Camussi G. Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation. Prostaglandins. 1980;20(5):781-791. https://doi.org/10.1016/0090-6980(80)90133-1
Bussolino, F. ; Camussi, G. / Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation. In: Prostaglandins. 1980 ; Vol. 20, No. 5. pp. 781-791.
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