Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation

F. Bussolino, G. Camussi

Research output: Contribution to journalArticle

Abstract

In this paper, the effect of prostacyclin (PGI2) on the aggregation induced by Platelet-activating factor (PAF), a phospholipid mediator of anaphylaxis, was studied. Synthetic PGI2 and PGI2-like activity generated from rabbit aorta were demonstrated to be effective inhibitors of PAF-induced rabbit platelet aggregation and release of 3H-serotonin (3H-5HT).

Original languageEnglish
Pages (from-to)781-791
Number of pages11
JournalProstaglandins
Volume20
Issue number5
DOIs
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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