Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation

F. Bussolino; G. Camussi

doi:10.1016/0090-6980(80)90133-1

Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation

F. Bussolino, G. Camussi

Istituto Oncologico Candiolo

Research output: Contribution to journal › Article

Abstract

In this paper, the effect of prostacyclin (PGI₂) on the aggregation induced by Platelet-activating factor (PAF), a phospholipid mediator of anaphylaxis, was studied. Synthetic PGI₂ and PGI₂-like activity generated from rabbit aorta were demonstrated to be effective inhibitors of PAF-induced rabbit platelet aggregation and release of ³H-serotonin (³H-5HT).

Original language	English
Pages (from-to)	781-791
Number of pages	11
Journal	Prostaglandins
Volume	20
Issue number	5
DOIs	https://doi.org/10.1016/0090-6980(80)90133-1
Publication status	Published - 1980

ASJC Scopus subject areas

Biochemistry
Endocrinology

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Bussolino, F., & Camussi, G. (1980). Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation. Prostaglandins, 20(5), 781-791. https://doi.org/10.1016/0090-6980(80)90133-1

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