TY - JOUR
T1 - Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy)
AU - Ortolani, Paolo
AU - Ardissino, Diego
AU - Cavallini, Claudio
AU - Bramucci, Ezio
AU - Indolfi, Ciro
AU - Aquilina, Matteo
AU - Marzocchi, Antonio
PY - 2005/11/15
Y1 - 2005/11/15
N2 - Randomized clinical trials have shown that sirolimus-eluting stents (SESs) decrease restenosis rates compared with bare metal stents (BMSs), but their efficacy among patients who have diabetes mellitus remains to be established. This study investigated the effect of SES implantation in a high-risk population (i.e., patients who had diabetes and small coronary vessel disease). For this purpose, we analyzed outcomes of the subset of patients who had diabetes and were enrolled in the SES-SMART, a randomized trial that compared the results of implantation of SESs and BMSs in small coronary arteries. Twenty-nine patients who had diabetes were originally randomized to receive SESs and 45 patients received BMSs. The use of SESs was associated with ∼60% decreases in the relative incidence of in-segment angiographic restenosis (63% vs 25%, p = 0.003) and in-segment late loss (0.76 vs 0.28 mm, p
AB - Randomized clinical trials have shown that sirolimus-eluting stents (SESs) decrease restenosis rates compared with bare metal stents (BMSs), but their efficacy among patients who have diabetes mellitus remains to be established. This study investigated the effect of SES implantation in a high-risk population (i.e., patients who had diabetes and small coronary vessel disease). For this purpose, we analyzed outcomes of the subset of patients who had diabetes and were enrolled in the SES-SMART, a randomized trial that compared the results of implantation of SESs and BMSs in small coronary arteries. Twenty-nine patients who had diabetes were originally randomized to receive SESs and 45 patients received BMSs. The use of SESs was associated with ∼60% decreases in the relative incidence of in-segment angiographic restenosis (63% vs 25%, p = 0.003) and in-segment late loss (0.76 vs 0.28 mm, p
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U2 - 10.1016/j.amjcard.2005.07.049
DO - 10.1016/j.amjcard.2005.07.049
M3 - Article
C2 - 16275185
AN - SCOPUS:27644462729
VL - 96
SP - 1393
EP - 1398
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 10
ER -