Abstract
The influence of tonic sympathetic and parasympathetic nervous system activity on ventricular refractory period duration was studied in 13 mongrel dogs. Strength-interval curves were obtained from the apex of the right ventricular endocardium with a transvenous bipolar catheter. The effects of sympathetic activity were assessed by unilateral and bilateral stellectomies and tonic vagal effects were studied by inducing cholinergic blockade with atropine (0.2 mg/kg) and by sectioning the cervical vagi bilaterally. Right stellectomy shifted the strength-interval curve 3-5 msec earlier (P
Original language | English |
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Pages (from-to) | 536-540 |
Number of pages | 5 |
Journal | Circulation Research |
Volume | 40 |
Issue number | 6 |
Publication status | Published - 1977 |
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine