Effect of steroid and high-dose immunoglobulin therapy on opsoclonus- myoclonus syndrome occurring in neuroblastoma

E. Veneselli; M. Conte; R. Biancheri; A. Acquaviva; B. De Bernardi

doi:10.1002/(SICI)1096-911X(199801)30:1<15::AID-MPO6>3.0.CO;2-3

Effect of steroid and high-dose immunoglobulin therapy on opsoclonus- myoclonus syndrome occurring in neuroblastoma

E. Veneselli, M. Conte, R. Biancheri, A. Acquaviva, B. De Bernardi

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

The authors describe a case of an 8-month-old boy with opsoclonus- myoclonus syndrome (OMS) and coincident unresectable neuroblastoma (NB). He achieved a complete remission for NB after 6 courses of standard-dose chemotherapy without significant neurological improvement despite the use of steroids and high-dose immunoglobulin (HIG), administered separately. Only the combined treatment with these two drugs induced a complete disappearance of neurological symptoms. On the basis of this experience, the authors suggest the association of steroids plus HIG for the treatment of OMS in patients not responsive to conventional first line therapy with steroids.

Original language	English
Pages (from-to)	15-17
Number of pages	3
Journal	Medical and Pediatric Oncology
Volume	30
Issue number	1
DOIs	https://doi.org/10.1002/(SICI)1096-911X(199801)30:1<15::AID-MPO6>3.0.CO;2-3
Publication status	Published - 1997

Keywords

Neuroblastoma
Opsomyoclonus syndrome
Treatment

ASJC Scopus subject areas

Cancer Research
Oncology
Pediatrics, Perinatology, and Child Health

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abstract = "The authors describe a case of an 8-month-old boy with opsoclonus- myoclonus syndrome (OMS) and coincident unresectable neuroblastoma (NB). He achieved a complete remission for NB after 6 courses of standard-dose chemotherapy without significant neurological improvement despite the use of steroids and high-dose immunoglobulin (HIG), administered separately. Only the combined treatment with these two drugs induced a complete disappearance of neurological symptoms. On the basis of this experience, the authors suggest the association of steroids plus HIG for the treatment of OMS in patients not responsive to conventional first line therapy with steroids.",

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AU - Veneselli, E.

AU - Conte, M.

AU - Biancheri, R.

AU - Acquaviva, A.

AU - De Bernardi, B.

PY - 1997

Y1 - 1997

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AB - The authors describe a case of an 8-month-old boy with opsoclonus- myoclonus syndrome (OMS) and coincident unresectable neuroblastoma (NB). He achieved a complete remission for NB after 6 courses of standard-dose chemotherapy without significant neurological improvement despite the use of steroids and high-dose immunoglobulin (HIG), administered separately. Only the combined treatment with these two drugs induced a complete disappearance of neurological symptoms. On the basis of this experience, the authors suggest the association of steroids plus HIG for the treatment of OMS in patients not responsive to conventional first line therapy with steroids.

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KW - Opsomyoclonus syndrome

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Effect of steroid and high-dose immunoglobulin therapy on opsoclonus- myoclonus syndrome occurring in neuroblastoma

Abstract

Keywords

ASJC Scopus subject areas

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