Abstract
This study evaluated the effect of telmisartan, ramipril, and amlodipine on atrial fibrillation (AF) recurrence and severity in hypertensive patients with metabolic syndrome. A total of 391 hypertensive outpatients with metabolic syndrome, in sinus rhythm but with at least 2 episodes of AF in the previous 6 months were randomized to telmisartan, ramipril, or amlodipine for 1 year. At the first AF, ventricular rate (VR) and plasma cardiac troponin I (TnI) were evaluated. P-wave dispersion (PWD) and procollagen type I carboxy-terminal peptide (PIP) were evaluated before and after 12 months of treatment. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were similarly and significantly reduced by all treatments (P
Original language | English |
---|---|
Pages (from-to) | 34-43 |
Number of pages | 10 |
Journal | Journal of Cardiovascular Pharmacology and Therapeutics |
Volume | 17 |
Issue number | 1 |
DOIs | |
Publication status | Published - Mar 2012 |
Keywords
- amlodipine
- atrial fibrillation
- hypertension
- ramipril
- telmisartan
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Cardiology and Cardiovascular Medicine