Effect of telmisartan on paroxysmal atrial fibrillation recurrence in hypertensive patients with normal or increased left atrial size

Roberto Fogari, Annalisa Zoppi, Pamela Maffioli, Amedeo Mugellini, Paola Preti, Tiziano Perrone, Giuseppe Derosa

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Hypertension is the most prevalent and potentially modifiable risk factor for atrial fibrillation (AF). In a previous secondary prevention study, the authors observed that the angiotensin II receptor blocker telmisartan was more effective than the calcium channel blocker amlodipine in preventing AF relapse in hypertensive patients with normal atrial size. Hypothesis: Telmisartan may be more effective than amlodipine in preventing AF recurrence in hypertensive patients with paroxysmal AF and normal or increased left atrial dimension (LAD). Methods: The authors assigned 378 mild hypertensive outpatients in sinus rhythm, but with ≥2 episodes of AF in the previous 6 months, to 1 of 2 groups. Group 1 comprised patients with LAD 40 mm and 45 mm and

Original languageEnglish
Pages (from-to)359-364
Number of pages6
JournalClinical Cardiology
Volume35
Issue number6
DOIs
Publication statusPublished - 2012

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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