Effect of the enhancement of the cholinergic tone by pyridostigmine on the exercise-induced growth hormone release in man

Marco Cappa, A. Grossi, S. Benedetti, F. Drago, S. Loche, E. Ghigo

Research output: Contribution to journalArticle

Abstract

We have evaluated the effect of pyridostigmine (PD), a cholinergic agonist, on the growth hormone (GH) response to physical exercise (EXC) in nine healthy volunteers. PD administration and EXC caused a similar increase of GH secretion to mean (±SE) peak values of 5.3±0.9 and 6.5±1.2 μg/l, respectively. Pretreatment with PD caused a significant augmentation of the EXC-induced GH release evaluated both as maximum peak (13.5±2.1 μg/l, p

Original languageEnglish
Pages (from-to)421-424
Number of pages4
JournalJournal of Endocrinological Investigation
Volume16
Issue number6
DOIs
Publication statusPublished - 1993

Keywords

  • GH
  • physical exercise
  • pyridostigmine
  • somatostatin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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