TY - JOUR
T1 - Effect of the postural challenge on the dependence of the cardiovascular control complexity on age
AU - Catai, Aparecida M.
AU - Takahashi, Anielle C M
AU - Perseguini, Natália M.
AU - Milan, Juliana C.
AU - Minatel, Vinicius
AU - Rehder-Santos, Patrícia
AU - Marchi, Andrea
AU - Bari, Vlasta
AU - Porta, Alberto
PY - 2014
Y1 - 2014
N2 - Short-term complexity of heart period (HP) and systolic arterial pressure (SAP) was computed to detect age and gender influences over cardiovascular control in resting supine condition (REST) and during standing (STAND). Healthy subjects (n = 110, men = 55) were equally divided into five groups (21-30; 31-40; 41-50; 51-60; and 61-70 years of age). HP and SAP series were recorded for 15 min at REST and during STAND. A normalized complexity index (NCI) based on conditional entropy was assessed. At REST we found that both NCIHP and NCISAP decreased with age in the overall population, but only women were responsible for this trend. During STAND we observed that both NCIHP and NCISAP were unrelated to age in the overall population, even when divided by gender. When the variation of NCI in response to STAND (ΔNCI = NCI at REST-NCI during STAND) was computed individually, we found that ΔNCIHP progressively decreased with age in the overall population, and women were again responsible for this trend. Conversely, ΔNCISAP was unrelated to age and gender. This study stresses that the complexity of cardiovascular control and its ability to respond to stressors are more importantly lost with age in women than in men.
AB - Short-term complexity of heart period (HP) and systolic arterial pressure (SAP) was computed to detect age and gender influences over cardiovascular control in resting supine condition (REST) and during standing (STAND). Healthy subjects (n = 110, men = 55) were equally divided into five groups (21-30; 31-40; 41-50; 51-60; and 61-70 years of age). HP and SAP series were recorded for 15 min at REST and during STAND. A normalized complexity index (NCI) based on conditional entropy was assessed. At REST we found that both NCIHP and NCISAP decreased with age in the overall population, but only women were responsible for this trend. During STAND we observed that both NCIHP and NCISAP were unrelated to age in the overall population, even when divided by gender. When the variation of NCI in response to STAND (ΔNCI = NCI at REST-NCI during STAND) was computed individually, we found that ΔNCIHP progressively decreased with age in the overall population, and women were again responsible for this trend. Conversely, ΔNCISAP was unrelated to age and gender. This study stresses that the complexity of cardiovascular control and its ability to respond to stressors are more importantly lost with age in women than in men.
KW - Aging
KW - Autonomic nervous system
KW - Blood pressure variability
KW - Complexity
KW - Corrected conditional entropy
KW - Gender
KW - Heart rate variability
KW - Standing
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U2 - 10.3390/e16126686
DO - 10.3390/e16126686
M3 - Article
AN - SCOPUS:84920911226
VL - 16
SP - 6686
EP - 6704
JO - Entropy
JF - Entropy
SN - 1099-4300
IS - 12
ER -