Abstract
The urotensin system has been hypothesized to play an important role in the pathophysiology of diabetic nephropathy. In this multicenter, randomized, double-blind, placebo-controlled, 2-period crossover study, the effects of the urotensin receptor antagonist palosuran on urinary albumin excretion and blood pressure in hypertensive patients with type 2 diabetic nephropathy treated with a single blocker of the renin-angiotensin-aldosterone system were assessed. Patients with 24-hour albuminuria >0.5 and 135 and 85 and
Original language | English |
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Pages (from-to) | 1206-1209 |
Number of pages | 4 |
Journal | Hypertension |
Volume | 55 |
Issue number | 5 |
DOIs | |
Publication status | Published - May 2010 |
Keywords
- Albuminuria
- Diabetic nephropathy
- Hypertension
- Palosuran
- RAAS blockade
- Urotensin antagonist
ASJC Scopus subject areas
- Internal Medicine