Abstract
The effect of the acute administration of three serotonin antagonists on plasma PRL levels and on the PRL response to suckling was investigated in a group of puerperal women. A single oral dose of metergoline or methysergide induced a significant decrease of plasma PRL levels and abolished that PRL response to suckling. Cyproheptadine administration did not modify either the plasma PRL levels or the PRL response to suckling. These results are discussed in light of the known pharmacological properties of the three antiserotonergic drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 335-337 |
| Number of pages | 3 |
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 48 |
| Issue number | 2 |
| Publication status | Published - 1979 |
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ASJC Scopus subject areas
- Biochemistry
- Endocrinology, Diabetes and Metabolism
Cite this
Effect of three serotonin antagonists on plasma prolactin response to suckling in puerperal women. / Crosignani, P. G.; Lombroso, G. C.; Mattei, A.; Caccamo, A.; Trojsi, L.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 48, No. 2, 1979, p. 335-337.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of three serotonin antagonists on plasma prolactin response to suckling in puerperal women
AU - Crosignani, P. G.
AU - Lombroso, G. C.
AU - Mattei, A.
AU - Caccamo, A.
AU - Trojsi, L.
PY - 1979
Y1 - 1979
N2 - The effect of the acute administration of three serotonin antagonists on plasma PRL levels and on the PRL response to suckling was investigated in a group of puerperal women. A single oral dose of metergoline or methysergide induced a significant decrease of plasma PRL levels and abolished that PRL response to suckling. Cyproheptadine administration did not modify either the plasma PRL levels or the PRL response to suckling. These results are discussed in light of the known pharmacological properties of the three antiserotonergic drugs.
AB - The effect of the acute administration of three serotonin antagonists on plasma PRL levels and on the PRL response to suckling was investigated in a group of puerperal women. A single oral dose of metergoline or methysergide induced a significant decrease of plasma PRL levels and abolished that PRL response to suckling. Cyproheptadine administration did not modify either the plasma PRL levels or the PRL response to suckling. These results are discussed in light of the known pharmacological properties of the three antiserotonergic drugs.
UR - http://www.scopus.com/inward/record.url?scp=0018394481&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018394481&partnerID=8YFLogxK
M3 - Article
C2 - 429487
AN - SCOPUS:0018394481
VL - 48
SP - 335
EP - 337
JO - Journal of Clinical Endocrinology and Metabolism
JF - Journal of Clinical Endocrinology and Metabolism
SN - 0021-972X
IS - 2
ER -