The effect of the acute administration of three serotonin antagonists on plasma PRL levels and on the PRL response to suckling was investigated in a group of puerperal women. A single oral dose of metergoline or methysergide induced a significant decrease of plasma PRL levels and abolished that PRL response to suckling. Cyproheptadine administration did not modify either the plasma PRL levels or the PRL response to suckling. These results are discussed in light of the known pharmacological properties of the three antiserotonergic drugs.
|Number of pages||3|
|Journal||Journal of Clinical Endocrinology and Metabolism|
|Publication status||Published - 1979|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism