Effect of ursodeoxycholic acid (UDCA) on dyspepsia in patients with gallstones or other biliary tract anomalies

P. Bianchi, D. Conte, L. Sironi

Research output: Contribution to journalArticle

Abstract

A doubel-blind controlled trial was carried in two groups of dyspeptic patients affected by biliary tract conditions with or without gallstones to study the effect of ursodeoxycholic acid (UDCA) on dyspeptic and painful disturbances. The UDCA was compared to placebo according to a 'between subjects' design; the treatment schedule was one capsule or UDCA 150 mg or placebo twice a day during 14 days. The results show a highly significant effect of UDCA compared to placebo with a remarkable improvement of the symptoms after a very short duration of treatment. UDCA appears very useful in the treatment of biliary dyspepsia although its exact mode of action requires further investigations.

Original languageEnglish
Pages (from-to)230-233
Number of pages4
JournalCurrent Therapeutic Research
Volume26
Issue number2
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Medicine(all)

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