Effect of verapamil on allergen-induced asthma in patients with respiratory allergy

A. Miadonna, A. Tedeschi, E. Leggieri, M. Cottini, M. Restuccia, C. Bianchini

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Specific degranulation of mast cells and basophils depends upon transmembrane calcium flow. In the present studies the protective effect of the calcium-antagonist drug verapamil against allergen-induced asthma was assessed in eight atopic patients. The results of this study showed that verapamil, administered both orally or by aerosol, can prevent the specific bronchoconstriction.

Original languageEnglish
Pages (from-to)201-204
Number of pages4
JournalAnnals of Allergy
Volume51
Issue number2 I
Publication statusPublished - 1983

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Verapamil
Allergens
Hypersensitivity
Asthma
Calcium
Bronchoconstriction
Basophils
Aerosols
Mast Cells
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Miadonna, A., Tedeschi, A., Leggieri, E., Cottini, M., Restuccia, M., & Bianchini, C. (1983). Effect of verapamil on allergen-induced asthma in patients with respiratory allergy. Annals of Allergy, 51(2 I), 201-204.

Effect of verapamil on allergen-induced asthma in patients with respiratory allergy. / Miadonna, A.; Tedeschi, A.; Leggieri, E.; Cottini, M.; Restuccia, M.; Bianchini, C.

In: Annals of Allergy, Vol. 51, No. 2 I, 1983, p. 201-204.

Research output: Contribution to journalArticle

Miadonna, A, Tedeschi, A, Leggieri, E, Cottini, M, Restuccia, M & Bianchini, C 1983, 'Effect of verapamil on allergen-induced asthma in patients with respiratory allergy', Annals of Allergy, vol. 51, no. 2 I, pp. 201-204.
Miadonna A, Tedeschi A, Leggieri E, Cottini M, Restuccia M, Bianchini C. Effect of verapamil on allergen-induced asthma in patients with respiratory allergy. Annals of Allergy. 1983;51(2 I):201-204.
Miadonna, A. ; Tedeschi, A. ; Leggieri, E. ; Cottini, M. ; Restuccia, M. ; Bianchini, C. / Effect of verapamil on allergen-induced asthma in patients with respiratory allergy. In: Annals of Allergy. 1983 ; Vol. 51, No. 2 I. pp. 201-204.
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