Azione delle acque arsenicali-ferruginose sulla lesione psoriasica: Un approccio istopatologico, immunoistochimico e strumentale non invasivo sui loro effetti

Translated title of the contribution: Effectiveness of arsenical-ferrouginous waters on psoriasis: Histologic, immunohistochemical and non-invasive assessment

G. P. Vignoli, O. Ciocca, D. Trespiolli, A. Selmi, R. Rosso, G. Borroni

Research output: Contribution to journalArticle

Abstract

Aim. The aim of this study was to evaluate the effective efficacy on psoriasis of arsenical-ferrouginous water from Terme di Levico e Vetriolo (Levico and Vetriolo Spa). Methods. The study was performed using 3 distinct approaches: the non-invasive, instrumental approach, evaluating the transepidermal water loss (TEWL) and superficial blood flow (laser-Doppler technology); and the histopatology, and the immunohistochemical techniques. We examined 40 volunteers (27 males and 13 females), age range 18 and 78 (mean 49 years), with a diagnosis of mild psoriasis, without any local or systemic treatment for at least 30 days before double-blind trial recruitment. Results. After a cycle of 12 applications there were no substantial clinical alterations, while there was a statistically significant TEWL decrease (P

Original languageItalian
Pages (from-to)165-173
Number of pages9
JournalGiornale Italiano di Dermatologia e Venereologia
Volume140
Issue number2
Publication statusPublished - 2005

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ASJC Scopus subject areas

  • Dermatology

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