Eight patients (5 males and 3 females, mean age 11.89±5.21 years) affected by epileptic encephalopathy underwent a clinical and EEG study before and after add-on treatment with felbamate (FBM). A reduction in seizure frequency has been observed in 4 patients. A reduction of the average interictal paroxysmal activity after 1 month of treatment was found during sleep, in 6 subjects, and during wakefulness, in 4 subjects. This preliminary study suggests that FBM is effective in the short term also in some epileptic syndromes of the infancy generally considered as intractable.
|Translated title of the contribution||Effectiveness of felbamate in epileptic encephalopathies: A clinical and EEG study|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1996|
ASJC Scopus subject areas
- Clinical Neurology