Effectiveness of frequency-modulated electromagnetic neural stimulation in the treatment of painful diabetic neuropathy

E. Bosi, M. Conti, C. Vermigli, G. Cazzetta, E. Peretti, M. C. Cordoni, G. Galimberti, L. Scionti

Research output: Contribution to journalArticle

Abstract

Aims/hypothesis: The largely unsatisfactory results reported for the pharmacological treatment of diabetic neuropathy has spurred the search for alternative therapies. The aim of this study was to evaluate the efficacy of frequency-modulated electromagnetic neural stimulation (FREMS) as a novel treatment for painful diabetic neuropathy. Methods: Patients (n=31) with painful neuropathy associated with decreased nerve conduction velocity (25 V) were enrolled in a randomised, double-blind, crossover study designed to compare the effects of FREMS with those of placebo. Each patient received two series of ten treatments of either FREMS or placebo in random sequence, with each series lasting no more than 3 weeks. The primary efficacy end point was the change in pain measured by a visual analogue scale (VAS). Results: FREMS induced a significant reduction in daytime and night-time VAS pain score (all p

Original languageEnglish
Pages (from-to)817-823
Number of pages7
JournalDiabetologia
Volume48
Issue number5
DOIs
Publication statusPublished - May 2005

Keywords

  • Clinical trial
  • Diabetes
  • Electromagnetic stimulation
  • Painful neuropathy

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

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    Bosi, E., Conti, M., Vermigli, C., Cazzetta, G., Peretti, E., Cordoni, M. C., Galimberti, G., & Scionti, L. (2005). Effectiveness of frequency-modulated electromagnetic neural stimulation in the treatment of painful diabetic neuropathy. Diabetologia, 48(5), 817-823. https://doi.org/10.1007/s00125-005-1734-2