Effectiveness of frequency-modulated electromagnetic neural stimulation in the treatment of painful diabetic neuropathy

E. Bosi; M. Conti; C. Vermigli; G. Cazzetta; E. Peretti; M. C. Cordoni; G. Galimberti; L. Scionti

doi:10.1007/s00125-005-1734-2

Effectiveness of frequency-modulated electromagnetic neural stimulation in the treatment of painful diabetic neuropathy

E. Bosi, M. Conti, C. Vermigli, G. Cazzetta, E. Peretti, M. C. Cordoni, G. Galimberti, L. Scionti

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article

Abstract

Aims/hypothesis: The largely unsatisfactory results reported for the pharmacological treatment of diabetic neuropathy has spurred the search for alternative therapies. The aim of this study was to evaluate the efficacy of frequency-modulated electromagnetic neural stimulation (FREMS) as a novel treatment for painful diabetic neuropathy. Methods: Patients (n=31) with painful neuropathy associated with decreased nerve conduction velocity (25 V) were enrolled in a randomised, double-blind, crossover study designed to compare the effects of FREMS with those of placebo. Each patient received two series of ten treatments of either FREMS or placebo in random sequence, with each series lasting no more than 3 weeks. The primary efficacy end point was the change in pain measured by a visual analogue scale (VAS). Results: FREMS induced a significant reduction in daytime and night-time VAS pain score (all p

Original language	English
Pages (from-to)	817-823
Number of pages	7
Journal	Diabetologia
Volume	48
Issue number	5
DOIs	https://doi.org/10.1007/s00125-005-1734-2
Publication status	Published - May 2005

Keywords

Clinical trial
Diabetes
Electromagnetic stimulation
Painful neuropathy

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Internal Medicine

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Bosi, E., Conti, M., Vermigli, C., Cazzetta, G., Peretti, E., Cordoni, M. C., Galimberti, G., & Scionti, L. (2005). Effectiveness of frequency-modulated electromagnetic neural stimulation in the treatment of painful diabetic neuropathy. Diabetologia, 48(5), 817-823. https://doi.org/10.1007/s00125-005-1734-2

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AU - Cazzetta, G.

AU - Peretti, E.

AU - Cordoni, M. C.

AU - Galimberti, G.

AU - Scionti, L.

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