EFFICACIA DEL MAGNESIO IN UN CASO DI IPERTENSIONE POLMONARE NEONATALE RESISTENTE ALLE COMUNI TERAPIE

Translated title of the contribution: Effectiveness of magnesium in a neonatal pulmonary hypertension refractory to the usual therapies

F. Colonna, R. Giorgi, G. Ciana, A. Benettoni

Research output: Contribution to journalArticle

Abstract

We describe a premature baby with X pentasomy, having a severe pulmonary hypertension secondary to perinatal asphyxia and hyaline membrane disease which appeared to be refractory to conventional treatments (hyperventilation, tolazoline, prostacycline). Oxygenation and pulmonary hypertension rapidly improved after starting magnesium sulphate infusion (loading dose: 20 mg/kg e.v. of elementary Mg, followed by continuous infusion of 2-4 mg/kg/hr during 6 days). The therapy was associated with hypermagnesemia (5-7 mg/100 ml) and transitory side effects (hypocalcemia, muscular and bladder paresis, bradycardia without hemodynamic decompensation). We suggest that magnesium therapy might be considered in newborns with severe and persistent pulmonary hypertension.

Translated title of the contributionEffectiveness of magnesium in a neonatal pulmonary hypertension refractory to the usual therapies
Original languageItalian
Pages (from-to)553-555
Number of pages3
JournalMinerva Pediatrica
Volume46
Issue number12
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Effectiveness of magnesium in a neonatal pulmonary hypertension refractory to the usual therapies'. Together they form a unique fingerprint.

  • Cite this