TY - JOUR
T1 - Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis
T2 - A case report
AU - Lombardi, G.
AU - Cabano, R.
AU - Bollani, L.
AU - Del Forno, C.
AU - Stronati, M.
PY - 2009/5
Y1 - 2009/5
N2 - Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that develops in fatty areas during the first weeks of life after foetal distress or perinatal complications. Prognosis is generally good with complete regression, but it can be complicated by metabolic abnormalities like hypoglycemia, hypertriglyceridemia, thrombocytopenia, and also potentially life-threatening hypercalcemia. We report a case of severe hypercalcemia complicating SCFN in a newborn who was treated with hyperhydration, furosemide, prednisone, and pamidronate.
AB - Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that develops in fatty areas during the first weeks of life after foetal distress or perinatal complications. Prognosis is generally good with complete regression, but it can be complicated by metabolic abnormalities like hypoglycemia, hypertriglyceridemia, thrombocytopenia, and also potentially life-threatening hypercalcemia. We report a case of severe hypercalcemia complicating SCFN in a newborn who was treated with hyperhydration, furosemide, prednisone, and pamidronate.
KW - Hypercalcemia
KW - Newborn
KW - Pamidronate
KW - Subcutaneous fat necrosis
KW - Therapy
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U2 - 10.1007/s00431-008-0797-8
DO - 10.1007/s00431-008-0797-8
M3 - Article
C2 - 18726115
AN - SCOPUS:62949141168
VL - 168
SP - 625
EP - 627
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
SN - 0340-6199
IS - 5
ER -