Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure

Ioannis Iakovou, Giuseppe M. Sangiorgi, Goran Stankovic, Nicola Corvaja, Iassen Michev, Alaide Chieffo, Renata Rogacka, Giancarlo Vitrella, Flavio Airoldi, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

The impact of the use of sirolimus-eluting stents (SESs) in the treatment of in-stent restenosis in previously irradiated sites has not been adequately evaluated. Fifteen consecutive patients who underwent percutaneous coronary interventions using SESs in lesion sites previously intervened with intracoronary radiation therapy were identified. All stents were implanted successfully, and there were no major in-hospital complications. At 30-day follow-up, there was 1 case of subacute thrombosis that led to target lesion revascularization (TLR). At 6 months, 2 patients underwent TLR because of recurrent angina with angiographic restenosis, and 1 patient underwent target vessel revascularization distally to the SES site; no other major adverse cardiac events occurred at long-term follow-up (mean 17 ± 8 months).

Original languageEnglish
Pages (from-to)351-354
Number of pages4
JournalThe American Journal of Cardiology
Volume94
Issue number3
DOIs
Publication statusPublished - Aug 1 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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