Effectiveness of steroid treatment in myasthenia gravis: A retrospective study

V. Cosi, A. Citterio, M. Lombardi, G. Piccolo, A. Romani, A. Erbetta

Research output: Contribution to journalArticle

Abstract

The records of 142 patients with generalized autoimmune myasthenia gravis who had been treated with steroids as the single immunosuppressive agent, collected at regular intervals, were employed for a retrospective evaluation. The effectiveness of treatment was assessed after 24 months; the data from the 6th and 12th months were also considered. After 24 months, 63.4% of the whole sample had improved (33.8% were in clinical or pharmacological remission); 13.4% were unchanged or had worsened and 22.3% had moved to a different immunosuppressive treatment. The rate of positive outcome was higher in patients over the age of 40 at disease onset.

Original languageEnglish
Pages (from-to)33-39
Number of pages7
JournalActa Neurologica Scandinavica
Volume84
Issue number1
Publication statusPublished - 1991

Fingerprint

Myasthenia Gravis
Immunosuppressive Agents
Retrospective Studies
Steroids
Pharmacology
Therapeutics

Keywords

  • Myasthenia gravis
  • Retrospective study
  • Steroid treatment

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Cosi, V., Citterio, A., Lombardi, M., Piccolo, G., Romani, A., & Erbetta, A. (1991). Effectiveness of steroid treatment in myasthenia gravis: A retrospective study. Acta Neurologica Scandinavica, 84(1), 33-39.

Effectiveness of steroid treatment in myasthenia gravis : A retrospective study. / Cosi, V.; Citterio, A.; Lombardi, M.; Piccolo, G.; Romani, A.; Erbetta, A.

In: Acta Neurologica Scandinavica, Vol. 84, No. 1, 1991, p. 33-39.

Research output: Contribution to journalArticle

Cosi, V, Citterio, A, Lombardi, M, Piccolo, G, Romani, A & Erbetta, A 1991, 'Effectiveness of steroid treatment in myasthenia gravis: A retrospective study', Acta Neurologica Scandinavica, vol. 84, no. 1, pp. 33-39.
Cosi, V. ; Citterio, A. ; Lombardi, M. ; Piccolo, G. ; Romani, A. ; Erbetta, A. / Effectiveness of steroid treatment in myasthenia gravis : A retrospective study. In: Acta Neurologica Scandinavica. 1991 ; Vol. 84, No. 1. pp. 33-39.
@article{e40ac2332ea94875adca149a8ebd0ba7,
title = "Effectiveness of steroid treatment in myasthenia gravis: A retrospective study",
abstract = "The records of 142 patients with generalized autoimmune myasthenia gravis who had been treated with steroids as the single immunosuppressive agent, collected at regular intervals, were employed for a retrospective evaluation. The effectiveness of treatment was assessed after 24 months; the data from the 6th and 12th months were also considered. After 24 months, 63.4{\%} of the whole sample had improved (33.8{\%} were in clinical or pharmacological remission); 13.4{\%} were unchanged or had worsened and 22.3{\%} had moved to a different immunosuppressive treatment. The rate of positive outcome was higher in patients over the age of 40 at disease onset.",
keywords = "Myasthenia gravis, Retrospective study, Steroid treatment",
author = "V. Cosi and A. Citterio and M. Lombardi and G. Piccolo and A. Romani and A. Erbetta",
year = "1991",
language = "English",
volume = "84",
pages = "33--39",
journal = "Acta Neurologica Scandinavica",
issn = "0001-6314",
publisher = "Wiley Blackwell",
number = "1",

}

TY - JOUR

T1 - Effectiveness of steroid treatment in myasthenia gravis

T2 - A retrospective study

AU - Cosi, V.

AU - Citterio, A.

AU - Lombardi, M.

AU - Piccolo, G.

AU - Romani, A.

AU - Erbetta, A.

PY - 1991

Y1 - 1991

N2 - The records of 142 patients with generalized autoimmune myasthenia gravis who had been treated with steroids as the single immunosuppressive agent, collected at regular intervals, were employed for a retrospective evaluation. The effectiveness of treatment was assessed after 24 months; the data from the 6th and 12th months were also considered. After 24 months, 63.4% of the whole sample had improved (33.8% were in clinical or pharmacological remission); 13.4% were unchanged or had worsened and 22.3% had moved to a different immunosuppressive treatment. The rate of positive outcome was higher in patients over the age of 40 at disease onset.

AB - The records of 142 patients with generalized autoimmune myasthenia gravis who had been treated with steroids as the single immunosuppressive agent, collected at regular intervals, were employed for a retrospective evaluation. The effectiveness of treatment was assessed after 24 months; the data from the 6th and 12th months were also considered. After 24 months, 63.4% of the whole sample had improved (33.8% were in clinical or pharmacological remission); 13.4% were unchanged or had worsened and 22.3% had moved to a different immunosuppressive treatment. The rate of positive outcome was higher in patients over the age of 40 at disease onset.

KW - Myasthenia gravis

KW - Retrospective study

KW - Steroid treatment

UR - http://www.scopus.com/inward/record.url?scp=0025882697&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025882697&partnerID=8YFLogxK

M3 - Article

C2 - 1927259

AN - SCOPUS:0025882697

VL - 84

SP - 33

EP - 39

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

SN - 0001-6314

IS - 1

ER -