Effector pathways in immune mediated central nervous system demyelination

Bernd C. Kieseier, Maria K. Storch, Juan J. Archelos, Gianvito Martino, Hans Peter Hartung

Research output: Contribution to journalArticle

Abstract

Multiple sclerosis is generally regarded to be a primarily T-cell driven disease. Recent evidence has refocused interest on antibodies. Adhesion molecules, matrix metalloproteinases, chemokines and cytokines, and nitric oxide and oxygen metabolites all participate in the amplification and effector stages of the disease.

Original languageEnglish
Pages (from-to)323-336
Number of pages14
JournalCurrent Opinion in Neurology
Volume12
Issue number3
DOIs
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Neuroscience(all)

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