Effects of acute and long-term slow breathing exercise on muscle sympathetic nerve activity in untreated male patients with hypertension

Dagmara Hering, Wieslawa Kucharska, Tomas Kara, Virend K. Somers, Gianfranco Parati, Krzysztof Narkiewicz

Research output: Contribution to journalArticle


Objective: Acute slow breathing (SLOWB) affects sympathetic cardiovascular regulation, but its long-term effects are unknown. Using device-guided breathing we explored short-term and long-term SLOWB effects on blood pressure (BP), heart rate (HR) and muscle sympathetic nerve activity (MSNA) in essential hypertension. Methods: We measured BP, HR and MSNA in 10 hypertensive individuals at rest, during laboratory stressors, before and after acute SLOWB, and 8 weeks after SLOWB exercise. Twelve matched hypertensive controls underwent a similar protocol excluding SLOWB intervention. Office and 24-h BP were obtained at baseline and at follow-up. Results: Acute SLOWB had no influence on BP, HR, but decreased MSNA (P

Original languageEnglish
Pages (from-to)739-746
Number of pages8
JournalJournal of Hypertension
Issue number4
Publication statusPublished - Apr 2013



  • essential hypertension
  • laboratory stressors
  • slow breathing
  • sympathetic activity

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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