Effects of alendronate on bone loss in pre- and postmenopausal hyperthyroid women treated with methimazole

G. Lupoli, V. Nuzzo, C. Di Carlo, P. Affinito, M. Vollery, G. Vitale, E. Cascone, F. Arlotta, C. Nappi

Research output: Contribution to journalArticlepeer-review

Abstract

High levels of thyroid hormones accelerate bone turnover. The aim of the present study was to evaluate the effects of treatment with alendronate in patients affected by hyperthyroidism and osteoporosis. We studied 40 hyperthyroid patients with bone loss, divided into two groups according to menopausal state. Before treatment and after 6 and 12 months, serum thyroid hormones levels, serum osteocalcin level and bone mineral density were evaluated. In all patients we observed an increase in bone mineral density after treatment with alendronate, and a corresponding decrease in serum osteocalcin level.

Original languageEnglish
Pages (from-to)343-348
Number of pages6
JournalGynecological Endocrinology
Volume10
Issue number5
Publication statusPublished - 1996

Keywords

  • Bisphosphonate
  • Bone mineral density
  • Hyperthyroidism
  • Osteocalcin
  • Osteoporosis

ASJC Scopus subject areas

  • Endocrinology
  • Obstetrics and Gynaecology

Fingerprint Dive into the research topics of 'Effects of alendronate on bone loss in pre- and postmenopausal hyperthyroid women treated with methimazole'. Together they form a unique fingerprint.

Cite this