Effects of amlodipine-atorvastatin combination on inflammation markers and insulin sensitivity in normocholesterolemic obese hypertensive patients

Roberto Fogari, Paola Preti, Annalisa Zoppi, Pierangelo Lazzari, Luca Corradi, Elena Fogari, Leonardina Ciccarelli, Giuseppe Derosa

Research output: Contribution to journalArticle

Abstract

Objective: The objective of this study was to assess the effect of amlodipine-atorvastatin combination on plasma interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and insulin sensitivity in normocholesterolemic obese hypertensive patients. Materials and methods: After a 4-week placebo wash-out period, 50 normocholesterolemic [total cholesterol (TC) 2) hypertensive patients (DBP >90 and 140 and

Original languageEnglish
Pages (from-to)817-822
Number of pages6
JournalEuropean Journal of Clinical Pharmacology
Volume62
Issue number10
DOIs
Publication statusPublished - Oct 2006

Keywords

  • Amlodipine
  • Atorvastatin
  • Insulin sensitivity
  • Interleukin-6
  • Obesity
  • TNF-α

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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