Abstract
After acute myocardial infarction (AMI), rehabilitation with physical training increases parasympathetic tone. It is unknown whether such a favorable effect of exercise on the sympathovagal balance interacts with effects of other widespread therapies, such as β blockers. In 53 patients after a first, uncomplicated AMI, we studied the combined short- and long- term influence on heart rate variability (HRV) of rehabilitation and β blockade. Patients were divided into 3 groups: group 1 (n = 19) underwent rehabilitation with physical training; group 2 (n = 20) was taking β blockers and underwent rehabilitation; group 3 (n = 14) was taking β blockers and did not enter the rehabilitation program for logistic reasons. Patients were similar as to age, site of infarction, ejection fraction, left ventricular diameter, and baseline stress test duration. Measures of HRV (obtained from a 15-minute resting electrocardiogram) were the standard deviation of the mean RR interval (RRSD), the mean squared successive differences (MSSD), the percent of RR intervals differing >50 ms from the preceding one (pNN50), the low-(LF) and high-(HF) frequency components of the autoregressive power spectrum of the RR intervals and their ratio (LF/HF). Four weeks after AMI, there was less sympathetic predominance in groups 2 and 3 (i.e., patients taking β blockers [p
| Original language | English |
|---|---|
| Pages (from-to) | 834-840 |
| Number of pages | 7 |
| Journal | The American Journal of Cardiology |
| Volume | 81 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Apr 1 1998 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Effects of cardiac rehabilitation and beta-blocker therapy on heart rate variability after first acute myocardial infarction. / Malfatto, Gabriella; Facchini, Mario; Sala, Luca; Branzi, Giovanna; Bragato, Renato; Leonetti, Gastone.
In: The American Journal of Cardiology, Vol. 81, No. 7, 01.04.1998, p. 834-840.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of cardiac rehabilitation and beta-blocker therapy on heart rate variability after first acute myocardial infarction
AU - Malfatto, Gabriella
AU - Facchini, Mario
AU - Sala, Luca
AU - Branzi, Giovanna
AU - Bragato, Renato
AU - Leonetti, Gastone
PY - 1998/4/1
Y1 - 1998/4/1
N2 - After acute myocardial infarction (AMI), rehabilitation with physical training increases parasympathetic tone. It is unknown whether such a favorable effect of exercise on the sympathovagal balance interacts with effects of other widespread therapies, such as β blockers. In 53 patients after a first, uncomplicated AMI, we studied the combined short- and long- term influence on heart rate variability (HRV) of rehabilitation and β blockade. Patients were divided into 3 groups: group 1 (n = 19) underwent rehabilitation with physical training; group 2 (n = 20) was taking β blockers and underwent rehabilitation; group 3 (n = 14) was taking β blockers and did not enter the rehabilitation program for logistic reasons. Patients were similar as to age, site of infarction, ejection fraction, left ventricular diameter, and baseline stress test duration. Measures of HRV (obtained from a 15-minute resting electrocardiogram) were the standard deviation of the mean RR interval (RRSD), the mean squared successive differences (MSSD), the percent of RR intervals differing >50 ms from the preceding one (pNN50), the low-(LF) and high-(HF) frequency components of the autoregressive power spectrum of the RR intervals and their ratio (LF/HF). Four weeks after AMI, there was less sympathetic predominance in groups 2 and 3 (i.e., patients taking β blockers [p
AB - After acute myocardial infarction (AMI), rehabilitation with physical training increases parasympathetic tone. It is unknown whether such a favorable effect of exercise on the sympathovagal balance interacts with effects of other widespread therapies, such as β blockers. In 53 patients after a first, uncomplicated AMI, we studied the combined short- and long- term influence on heart rate variability (HRV) of rehabilitation and β blockade. Patients were divided into 3 groups: group 1 (n = 19) underwent rehabilitation with physical training; group 2 (n = 20) was taking β blockers and underwent rehabilitation; group 3 (n = 14) was taking β blockers and did not enter the rehabilitation program for logistic reasons. Patients were similar as to age, site of infarction, ejection fraction, left ventricular diameter, and baseline stress test duration. Measures of HRV (obtained from a 15-minute resting electrocardiogram) were the standard deviation of the mean RR interval (RRSD), the mean squared successive differences (MSSD), the percent of RR intervals differing >50 ms from the preceding one (pNN50), the low-(LF) and high-(HF) frequency components of the autoregressive power spectrum of the RR intervals and their ratio (LF/HF). Four weeks after AMI, there was less sympathetic predominance in groups 2 and 3 (i.e., patients taking β blockers [p
UR - http://www.scopus.com/inward/record.url?scp=0032054874&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032054874&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(98)00021-6
DO - 10.1016/S0002-9149(98)00021-6
M3 - Article
C2 - 9555771
AN - SCOPUS:0032054874
VL - 81
SP - 834
EP - 840
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 7
ER -