Abstract
Lamotrigine (LTG) is a new antiepileptic drug, currently used in medically intractable patients. We studied nocturnal sleep and daytime somnolence in 13 patients undergoing add-on therapy with LTG for seizures resistant to common antiepileptic drugs (AEDs). LTG caused a significant increase of REM sleep and a significant decrease of SWS, of the number of stage shifts and of the number of entries in REM. No significant changes were observed in daytime sleepiness and cognitive functions after 3 months of treatment. The increased stability of nocturnal sleep could play an important role in the anticonvulsant effect of LTG.
Translated title of the contribution | Effects of chronic treatment with Lamotrigine on nocturnal sleep and daytime sleepiness |
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Original language | Italian |
Pages (from-to) | 221-222 |
Number of pages | 2 |
Journal | Bollettino - Lega Italiana contro l'Epilessia |
Issue number | 95-96 |
Publication status | Published - 1996 |
ASJC Scopus subject areas
- Clinical Neurology